Continuous organocatalytic flow synthesis of 2-substituted oxazolidinones using carbon dioxide
Nicola Zanda, Leijie Zhou, Esther Alza, Arjan W. Kleij, Miquel À. Pericàs
Green Chemistry · 2022 · 10.1039/d2gc00503d
Abstract
A catalytic continuous flow approach towards pharmaceutically relevant oxazolidinones has been developed using epoxy alcohols and CO 2 as reagents, taking advantage of a stable, scalable and metal- and halide-free protocol.
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