I2-Mediated Diversity Oriented Diastereoselective Synthesis of Amino Acid Derived trans-2,5-Disubstituted Morpholines, Piperazines, and Thiomorpholines
Saurav Bera, Gautam Panda
ACS Combinatorial Science · 2012 · 10.1021/co200129t
★ 1.0
1 rating
5
:
Major extension (new functional group)
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4
:
Minor extension (no new functional group)
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3
:
Reproduced as published
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2
:
Reproduced with deviation
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1
:
Did not work
×1
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:
Extension failed / Inconclusive
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PhD student
13 Jul 2026
★ 1 : Did not work
I have tried the iodoetherification as suggested in the paper, with R = H and NBn instead of NTs. Unfortunately I only saw a mixture of unidentified products.
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