Metal-Free, Rapid, and Highly Chemoselective Reduction of Aromatic Nitro Compounds at Room Temperature

Mingyeong Jang, Taeho Lim, Byoung Yong Park, Min Su Han

The Journal of Organic Chemistry · 2022 · 10.1021/acs.joc.1c01431

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★ 5.0 1 rating
5 : Major extension (new functional group) ×1
4 : Minor extension (no new functional group)
3 : Reproduced as published
2 : Reproduced with deviation
1 : Did not work
: Extension failed / Inconclusive

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Industry / CRO chemist
21 Aug 2026
★ 5 : Major extension (new functional group)

Performed it on solid phase on a peptide.