Triphenylphosphine–iodine: an efficient reagent for the regioselective dehydration of tertiary alcohols
E.J. Alvarez-Manzaneda, R. Chahboun, E. Cabrera Torres, E. Alvarez, R. Alvarez-Manzaneda, A. Haidour, J. Ramos
Tetrahedron Letters · 2004 · 10.1016/j.tetlet.2004.04.058
★ 4.0
1 rating
5
:
Major extension (new functional group)
–
4
:
Minor extension (no new functional group)
×1
3
:
Reproduced as published
–
2
:
Reproduced with deviation
–
1
:
Did not work
–
–
:
Extension failed / Inconclusive
–
Community reviews (1)
Sort
Stars
Context
Industry / CRO chemist
09 Aug 2026
★ 4 : Minor extension (no new functional group)
The olefination reaction on sclerol glycol proceeded successfully; however, purification required reversed-phase chromatography, as the product was obtained with relatively low purity when purified by normal-phase chromatography using 100% heptane. The paper is also somewhat unclear regarding the experimental procedures, as it provides a general procedure rather than specific conditions for each individual compound.
Save to Library
Report a bug
Reporting an issue for DOI:
Describe the problem: wrong title, missing abstract, incorrect authors, or anything else that looks off.
Thank you for your report! We will look into it.
Report this content
Report submitted. Thanks for helping keep ChemRepro clean.